The Department of Biotechnology did not effectively manage the execution of its Medical Biotechnology programme. Critical processes such as assessment of project proposals, ensuring compliance to mandatory safety protocols, periodic monitoring of projects and timely evaluation of all completed projects was not done. The number of publications in high impact journals was very low, indicating poor quality of the projects. Financial management needed to be improved. Even after disbursement of ₹ 1203.40 crore on projects under Medical Biotechnology Programme, only one patent has been granted with no technology transfer, indicating poor planning and outcomes of the projects for translational research in the area of improving human health and wellness.