There is no single framework of National Disease Control Programme as such. It is a cluster of programmes encompassing a wide range of major diseases which have commenced at different periods of time and with different methodologies and approaches. All such programmes contribute eventually to the efforts of the Government to treat, prevent and control major diseases like Cataract Blindness, Tuberculosis, Leprosy and Acquired Immune Deficiency Syndrome (AIDS) in the country. Schemes relating to two of these major diseases, namely Blindness and Tuberculosis were selected in audit for review by the CAG of India, mainly because these diseases are geographically more wide-spread, the programmes have been in operation for a long period, using large sums of resources and have undergone significant policy changes over time. Section I deals with National Programme for Control of Blindness (NPCB) and Section II deals with National Tuberculosis Control Programme (NTCP).